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Crystallographic Evidence of Drastic Conformational Changes in the Active Site of a Flavin-Dependent N-Hydroxylase

[Image: see text] The soil actinomycete Kutzneria sp. 744 produces a class of highly decorated hexadepsipeptides, which represent a new chemical scaffold that has both antimicrobial and antifungal properties. These natural products, known as kutznerides, are created via nonribosomal peptide synthesi...

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Detaylı Bibliyografya
Asıl Yazarlar: Setser, Jeremy W., Heemstra, John R., Walsh, Christopher T., Drennan, Catherine L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2014
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179590/
https://ncbi.nlm.nih.gov/pubmed/25184411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500655q
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