PP2A-B56 opposes Mps1 phosphorylation of Knl1 and thereby promotes spindle assembly checkpoint silencing

The spindle assembly checkpoint (SAC) monitors correct attachment of chromosomes to microtubules, an important safeguard mechanism ensuring faithful chromosome segregation in eukaryotic cells. How the SAC signal is turned off once all the chromosomes have successfully attached to the spindle remains...

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Autores principales: Espert, Antonio, Uluocak, Pelin, Bastos, Ricardo Nunes, Mangat, Davinderpreet, Graab, Philipp, Gruneberg, Ulrike
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178970/
https://ncbi.nlm.nih.gov/pubmed/25246613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201406109
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