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Cdc42 and formin activity control non-muscle myosin dynamics during Drosophila heart morphogenesis

During heart formation, a network of transcription factors and signaling pathways guide cardiac cell fate and differentiation, but the genetic mechanisms orchestrating heart assembly and lumen formation remain unclear. Here, we show that the small GTPase Cdc42 is essential for Drosophila melanogaste...

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Main Authors: Vogler, Georg, Liu, Jiandong, Iafe, Timothy W., Migh, Ede, Mihály, József, Bodmer, Rolf
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178965/
https://ncbi.nlm.nih.gov/pubmed/25267295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201405075
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