Cdc42 and formin activity control non-muscle myosin dynamics during Drosophila heart morphogenesis

During heart formation, a network of transcription factors and signaling pathways guide cardiac cell fate and differentiation, but the genetic mechanisms orchestrating heart assembly and lumen formation remain unclear. Here, we show that the small GTPase Cdc42 is essential for Drosophila melanogaste...

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Bibliografiske detaljer
Main Authors: Vogler, Georg, Liu, Jiandong, Iafe, Timothy W., Migh, Ede, Mihály, József, Bodmer, Rolf
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2014
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178965/
https://ncbi.nlm.nih.gov/pubmed/25267295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201405075
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