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IL-1 Blockade in Autoinflammatory Syndromes
Monogenic autoinflammatory syndromes present with excessive systemic inflammation including fever, rashes, arthritis, and organ-specific inflammation and are caused by defects in single genes encoding proteins that regulate innate inflammatory pathways. Pathogenic variants in two interleukin-1 (IL-1...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
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2014
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4178953/ https://ncbi.nlm.nih.gov/pubmed/24422572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-med-061512-150641 |
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