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Voltage-dependent regulation of Ca(V)2.2 channels by G(q)-coupled receptor is facilitated by membrane-localized β subunit
G protein–coupled receptors (GPCRs) signal through molecular messengers, such as Gβγ, Ca(2+), and phosphatidylinositol 4,5-bisphosphate (PIP(2)), to modulate N-type voltage-gated Ca(2+) (Ca(V)2.2) channels, playing a crucial role in regulating synaptic transmission. However, the cellular pathways th...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4178937/ https://ncbi.nlm.nih.gov/pubmed/25225550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411245 |
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