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TRIM13 Is a Negative Regulator of MDA5-Mediated Type I Interferon Production
Retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated gene 5 (MDA5) are essential intracellular detectors of viral RNA. They contribute to the type I interferon (IFN) response that is crucial for host defense against viral infections. Given the potent antiviral and proinflam...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4178852/ https://ncbi.nlm.nih.gov/pubmed/25008915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02593-13 |
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