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Structure Analysis of the Major Capsid Proteins of Human Polyomaviruses 6 and 7 Reveals an Obstructed Sialic Acid Binding Site

Human polyomavirus 6 (HPyV6) and HPyV7 are commonly found on human skin. We have determined the X-ray structures of their major capsid protein, VP1, at resolutions of 1.8 and 1.7 Å, respectively. In polyomaviruses, VP1 commonly determines antigenicity as well as cell-surface receptor specificity, an...

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Bibliografiset tiedot
Päätekijät: Ströh, Luisa J., Neu, Ursula, Blaum, Bärbel S., Buch, Michael H. C., Garcea, Robert L., Stehle, Thilo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178836/
https://ncbi.nlm.nih.gov/pubmed/25008942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01084-14
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