Potent Neutralization of Vaccinia Virus by Divergent Murine Antibodies Targeting a Common Site of Vulnerability in L1 Protein

Vaccinia virus (VACV) L1 is an important target for viral neutralization and has been included in multicomponent DNA or protein vaccines against orthopoxviruses. To further understand the protective mechanism of the anti-L1 antibodies, we generated five murine anti-L1 monoclonal antibodies (MAbs), w...

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Detaylı Bibliyografya
Asıl Yazarlar: Kaever, Thomas, Meng, Xiangzhi, Matho, Michael H., Schlossman, Andrew, Li, Sheng, Sela-Culang, Inbal, Ofran, Yanay, Buller, Mark, Crump, Ryan W., Parker, Scott, Frazier, April, Crotty, Shane, Zajonc, Dirk M., Peters, Bjoern, Xiang, Yan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2014
Konular:
Pathogenesis and Immunity
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178804/
https://ncbi.nlm.nih.gov/pubmed/25031354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01491-14
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