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Mutagenesis of the Catalytic and Cleavage Site Residues of the Hypovirus Papain-Like Proteases p29 and p48 Reveals Alternative Processing and Contributions to Optimal Viral RNA Accumulation

The positive-stranded RNA genome of the prototypic virulence-attenuating hypovirus CHV-1/EP713 contains two open reading frames (ORF), each encoding an autocatalytic papain-like leader protease. Protease p29, derived from the N-terminal portion of ORF A, functions as a suppressor of RNA silencing, w...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jensen, Kenneth S., Nuss, Donald L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178723/
https://ncbi.nlm.nih.gov/pubmed/25100848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01489-14
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