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Mutagenesis of the Catalytic and Cleavage Site Residues of the Hypovirus Papain-Like Proteases p29 and p48 Reveals Alternative Processing and Contributions to Optimal Viral RNA Accumulation
The positive-stranded RNA genome of the prototypic virulence-attenuating hypovirus CHV-1/EP713 contains two open reading frames (ORF), each encoding an autocatalytic papain-like leader protease. Protease p29, derived from the N-terminal portion of ORF A, functions as a suppressor of RNA silencing, w...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4178723/ https://ncbi.nlm.nih.gov/pubmed/25100848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01489-14 |
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