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Tobacco exposure results in increased E6 and E7 oncogene expression, DNA damage and mutation rates in cells maintaining episomal human papillomavirus 16 genomes

High-risk human papillomavirus (HR-HPV) infections are necessary but insufficient agents of cervical and other epithelial cancers. Epidemiological studies support a causal, but ill-defined, relationship between tobacco smoking and cervical malignancies. In this study, we used mainstream tobacco smok...

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Detalhes bibliográficos
Main Authors: Wei, Lanlan, Griego, Anastacia M., Chu, Ming, Ozbun, Michelle A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178472/
https://ncbi.nlm.nih.gov/pubmed/25064354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu156
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