SUMOylation of the ING1b tumor suppressor regulates gene transcription

The INhibitor of Growth (ING) proteins are encoded as multiple isoforms in five ING genes (ING1 –5) and act as type II tumor suppressors. They are growth inhibitory when overexpressed and are frequently mislocalized or downregulated in several forms of cancer. ING1 and ING2 are stoichiometric member...

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Bibliographic Details
Main Authors: Satpathy, Shankha, Guérillon, Claire, Kim, Tae-Sun, Bigot, Nicolas, Thakur, Satbir, Bonni, Shirin, Riabowol, Karl, Pedeux, Rémy
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178466/
https://ncbi.nlm.nih.gov/pubmed/24903338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu126
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