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SUMOylation of the ING1b tumor suppressor regulates gene transcription
The INhibitor of Growth (ING) proteins are encoded as multiple isoforms in five ING genes (ING1 –5) and act as type II tumor suppressors. They are growth inhibitory when overexpressed and are frequently mislocalized or downregulated in several forms of cancer. ING1 and ING2 are stoichiometric member...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4178466/ https://ncbi.nlm.nih.gov/pubmed/24903338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu126 |
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