The Kidney Is the Principal Organ Mediating Klotho Effects

Klotho was discovered as an antiaging gene, and α-Klotho (Klotho) is expressed in multiple tissues with a broad set of biologic functions. Membrane-bound Klotho binds fibroblast growth factor 23 (FGF23), but a soluble form of Klotho is also produced by alternative splicing or cleavage of the extrace...

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Autori principali: Lindberg, Karolina, Amin, Risul, Moe, Orson W., Hu, Ming-Chang, Erben, Reinhold G., Östman Wernerson, Annika, Lanske, Beate, Olauson, Hannes, Larsson, Tobias E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2014
Soggetti:
Brief Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178446/
https://ncbi.nlm.nih.gov/pubmed/24854271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013111209
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