GLP-1R–Targeting Magnetic Nanoparticles for Pancreatic Islet Imaging

Noninvasive assessment of pancreatic β-cell mass would tremendously aid in managing type 1 diabetes (T1D). Toward this goal, we synthesized an exendin-4 conjugated magnetic iron oxide–based nanoparticle probe targeting glucagon-like peptide 1 receptor (GLP-1R), which is highly expressed on the surfa...

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Autori principali: Wang, Ping, Yoo, Byunghee, Yang, Jingsheng, Zhang, Xueli, Ross, Alana, Pantazopoulos, Pamela, Dai, Guangping, Moore, Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2014
Soggetti:
Technological Advances
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178324/
https://ncbi.nlm.nih.gov/pubmed/24458362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1543
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