RIG-I Self-Oligomerization Is Either Dispensable or Very Transient for Signal Transduction

Effective host defence against viruses depends on the rapid triggering of innate immunity through the induction of a type I interferon (IFN) response. To this end, microbe-associated molecular patterns are detected by dedicated receptors. Among them, the RIG-I-like receptors RIG-I and MDA5 activate...

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Bibliografiske detaljer
Main Authors: Louber, Jade, Kowalinski, Eva, Bloyet, Louis-Marie, Brunel, Joanna, Cusack, Stephen, Gerlier, Denis
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178188/
https://ncbi.nlm.nih.gov/pubmed/25259935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108770
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