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Direct Proof of the In Vivo Pathogenic Role of the AChR Autoantibodies from Myasthenia Gravis Patients

Several studies have suggested that the autoantibodies (autoAbs) against muscle acetylcholine receptor (AChR) of myasthenia gravis (MG) patients are the main pathogenic factor in MG; however, this belief has not yet been confirmed with direct observations. Although animals immunized with AChR or inj...

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Autors principals: Kordas, Gregory, Lagoumintzis, George, Sideris, Sotirios, Poulas, Konstantinos, Tzartos, Socrates J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178151/
https://ncbi.nlm.nih.gov/pubmed/25259739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108327
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