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Direct Proof of the In Vivo Pathogenic Role of the AChR Autoantibodies from Myasthenia Gravis Patients

Several studies have suggested that the autoantibodies (autoAbs) against muscle acetylcholine receptor (AChR) of myasthenia gravis (MG) patients are the main pathogenic factor in MG; however, this belief has not yet been confirmed with direct observations. Although animals immunized with AChR or inj...

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Detalhes bibliográficos
Main Authors: Kordas, Gregory, Lagoumintzis, George, Sideris, Sotirios, Poulas, Konstantinos, Tzartos, Socrates J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178151/
https://ncbi.nlm.nih.gov/pubmed/25259739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108327
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