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Multivariate Dimensionality Reduction Approaches to Identify Gene-Gene and Gene-Environment Interactions Underlying Multiple Complex Traits

The elusive but ubiquitous multifactor interactions represent a stumbling block that urgently needs to be removed in searching for determinants involved in human complex diseases. The dimensionality reduction approaches are a promising tool for this task. Many complex diseases exhibit composite synd...

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Bibliografiske detaljer
Main Authors: Xu, Hai-Ming, Sun, Xi-Wei, Qi, Ting, Lin, Wan-Yu, Liu, Nianjun, Lou, Xiang-Yang
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178067/
https://ncbi.nlm.nih.gov/pubmed/25259584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108103
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