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Mitf regulates osteoclastogenesis by modulating NFATc1 activity

Transcription factors Mitf and NFATc1 share many downstream targets that are critical for osteoclastogenesis. Since RANKL signals induce/activate both NFATc1 and Mitf isoform-E (Mitf-E), a tissue-restricted Mitf isoform in osteoclasts, it is plausible that the two factors work together to promote os...

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Détails bibliographiques
Auteurs principaux: Lu, Ssu-Yi, Li, Mengtao, Lin, Yi-Ling
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177974/
https://ncbi.nlm.nih.gov/pubmed/25152440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2014.08.018
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