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Mitf regulates osteoclastogenesis by modulating NFATc1 activity
Transcription factors Mitf and NFATc1 share many downstream targets that are critical for osteoclastogenesis. Since RANKL signals induce/activate both NFATc1 and Mitf isoform-E (Mitf-E), a tissue-restricted Mitf isoform in osteoclasts, it is plausible that the two factors work together to promote os...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4177974/ https://ncbi.nlm.nih.gov/pubmed/25152440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2014.08.018 |
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