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Deazaneplanocin A Is a Promising Drug to Kill Multiple Myeloma Cells in Their Niche
Tumoral plasma cells has retained stemness features and in particular, a polycomb-silenced gene expression signature. Therefore, epigenetic therapy could be a mean to fight for multiple myeloma (MM), still an incurable pathology. Deazaneplanocin A (DZNep), a S-adenosyl-L-homocysteine hydrolase inhib...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4177844/ https://ncbi.nlm.nih.gov/pubmed/25255316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107009 |
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