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Xanthene Derivatives Increase Glucose Utilization through Activation of LKB1-Dependent AMP-Activated Protein Kinase

5′ AMP-activated protein kinase (AMPK) is a highly conserved serine-threonine kinase that regulates energy expenditure by activating catabolic metabolism and suppressing anabolic pathways to increase cellular energy levels. Therefore AMPK activators are considered to be drug targets for treatment of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kwon, Yonghoon, Song, Parkyong, Yoon, Jong Hyuk, Ghim, Jaewang, Kim, Dayea, Kang, Byungjun, Lee, Taehoon G., Kim, Jin-Ah, Choi, Joong-Kwon, Youn, In Kwon, Lee, Hyeon-Kyu, Ryu, Sung Ho
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177559/
https://ncbi.nlm.nih.gov/pubmed/25250787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108771
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