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Slow growth of Mycobacterium tuberculosis at acidic pH is regulated by phoPR and host-associated carbon sources

During pathogenesis, Mycobacterium tuberculosis (Mtb) colonizes environments, such as the macrophage or necrotic granuloma, that are acidic and rich in cholesterol and fatty acids. The goal of this study was to examine how acidic pH and available carbon sources interact to regulate Mtb physiology. H...

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Main Authors: Baker, Jacob J., Johnson, Benjamin K., Abramovitch, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177513/
https://ncbi.nlm.nih.gov/pubmed/24975990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12688
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