Deletion of Serum Amyloid A3 Improves High Fat High Sucrose Diet-Induced Adipose Tissue Inflammation and Hyperlipidemia in Female Mice

Serum amyloid A (SAA) increases in response to acute inflammatory stimuli and is modestly and chronically elevated in obesity. SAA3, an inducible form of SAA, is highly expressed in adipose tissue in obese mice where it promotes monocyte chemotaxis, providing a mechanism for the macrophage accumulat...

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Detalhes bibliográficos
Main Authors: den Hartigh, Laura J., Wang, Shari, Goodspeed, Leela, Ding, Yilei, Averill, Michelle, Subramanian, Savitha, Wietecha, Tomasz, O'Brien, Kevin D., Chait, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177399/
https://ncbi.nlm.nih.gov/pubmed/25251243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108564
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