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The Scc2/Scc4 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions

The cohesin complex is at the heart of many chromosomal activities, including sister chromatid cohesion and transcriptional regulation(1-3). Cohesin loading onto chromosomes depends on the Scc2/Scc4 cohesin loader complex(4-6), but the chromatin features that form cohesin loading sites remain poorly...

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Detalhes bibliográficos
Main Authors: Lopez-Serra, Lidia, Kelly, Gavin, Patel, Harshil, Stewart, Aengus, Uhlmann, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177232/
https://ncbi.nlm.nih.gov/pubmed/25173104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3080
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