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Neurotrophins regulate ApoER2 proteolysis through activation of the Trk signaling pathway

BACKGROUND: ApoER2 and the neurotrophin receptors Trk and p75(NTR) are expressed in the CNS and regulate key functional aspects of neurons, including development, survival, and neuronal function. It is known that both ApoER2 and p75(NTR) are processed by metalloproteinases, followed by regulated int...

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Detalhes bibliográficos
Main Authors: Larios, Jorge A, Jausoro, Ignacio, Benitez, Maria-Luisa, Bronfman, Francisca C, Marzolo, Maria-Paz
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177048/
https://ncbi.nlm.nih.gov/pubmed/25233900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-15-108
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