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The significance of spliceosome mutations in chronic lymphocytic leukemia
Cellular proteins produced via alternative splicing, provide neoplastic cells with survival advantage and/or promote neoplastic cell proliferation. Pre-mRNA is spliced by the spliceosome consisting of large complexes of small nuclear RNA (snRNA) and protein subunits. Spliceosome gene mutations were...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4176818/ https://ncbi.nlm.nih.gov/pubmed/23270583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2012.742528 |
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