Clinical and molecular characteristics of XPO1 mutations in patients with chronic lymphocytic leukemia

The XPO1 (exportin) gene (also referred to as chromosome region maintenance 1; CRM1) is a karyopherin that exports proteins and RNA fragments from the nucleus into the cytoplasm.(1),(2) The human XPO1 gene, located on chromosome 2 (2p15), is believed to encode an oncogenic protein since many of the...

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Dades bibliogràfiques
Publicat a:Am J Hematol
Autors principals: Jain, Preetesh, Kanagal-Shamanna, Rashmi, Wierda, William, Keating, Michael, Sarwari, Nawid, Rozovski, Uri, Thompson, Philip, Burger, Jan, Kantarjian, Hagop, Patel, Keyur P., Medeiros, L. Jeffrey, Luthra, Rajyalakshmi, Estrov, Zeev
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073031/
https://ncbi.nlm.nih.gov/pubmed/27468087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.24496
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