DNA synthesis and topoisomerase inhibitors increase transduction by adeno-associated virus vectors.
Viral vectors based on adeno-associated virus (AAV) preferentially transduce cells in S phase of the cell cycle. We recently found that DNA-damaging agents increased the transduction of nondividing cells. However, the optimal concentrations were toxic to cells. Here we show that the transduction of...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
1995
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41768/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7777575/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.12.5719 |
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