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The effect of resveratrol and its methylthio-derivatives on EGFR and Stat3 activation in human HaCaT and A431 cells

Epidermal growth factor receptor (EGFR) interacting with Stat3 is considered to be an attractive therapeutic target. In the current study, we investigated the effect of resveratrol and its two 4′-methylthio-trans-stilbene derivatives (3-M-4′-MTS; S2) (3,5-DM-4″-MTS; S5) on EGFR and Stat3 activation...

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Библиографические подробности
Главные авторы: Cichocki, Michal, Szaefer, Hanna, Krajka-Kuźniak, Violetta, Baer-Dubowska, Wanda
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176574/
https://ncbi.nlm.nih.gov/pubmed/25063218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-014-2157-5
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