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The effect of resveratrol and its methylthio-derivatives on EGFR and Stat3 activation in human HaCaT and A431 cells

Epidermal growth factor receptor (EGFR) interacting with Stat3 is considered to be an attractive therapeutic target. In the current study, we investigated the effect of resveratrol and its two 4′-methylthio-trans-stilbene derivatives (3-M-4′-MTS; S2) (3,5-DM-4″-MTS; S5) on EGFR and Stat3 activation...

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Autors principals: Cichocki, Michal, Szaefer, Hanna, Krajka-Kuźniak, Violetta, Baer-Dubowska, Wanda
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176574/
https://ncbi.nlm.nih.gov/pubmed/25063218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-014-2157-5
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