Effects of 5-aza-2'-deoxycytidine and trichostatin A on high glucose- and interleukin-1β-induced secretory mediators from human retinal endothelial cells and retinal pigment epithelial cells

PURPOSE: We aimed to elucidate the effects of two epigenetic inhibitors, 5-aza-2’-deoxycytidine (5-aza-dC) and trichostatin A (TSA), on several key secretory mediators of diabetic retinopathy (DR) in human retinal endothelial cells (HRECs) and human retinal pigment epithelial (HRPE) cells treated wi...

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Détails bibliographiques
Auteurs principaux: Xie, Manyun, Tian, Jingyi, Luo, Yan, Wei, Liqing, Lin, Shaofen, Tang, Shibo
Format: Artigo
Langue:Inglês
Publié: Molecular Vision 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176430/
https://ncbi.nlm.nih.gov/pubmed/25352747
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