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A competitive formation of DNA:RNA hybrid G-quadruplex is responsible to the mitochondrial transcription termination at the DNA replication priming site

Human mitochondrial DNA contains a distinctive guanine-rich motif denoted conserved sequence block II (CSB II) that stops RNA transcription, producing prematurely terminated transcripts to prime mitochondrial DNA replication. Recently, we reported a general phenomenon that DNA:RNA hybrid G-quadruple...

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Detalhes bibliográficos
Main Authors: Zheng, Ke-wei, Wu, Ren-yi, He, Yi-de, Xiao, Shan, Zhang, Jia-yu, Liu, Jia-quan, Hao, Yu-hua, Tan, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176368/
https://ncbi.nlm.nih.gov/pubmed/25140009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku764
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