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Effects of supercoiling on enhancer–promoter contacts

Using Brownian dynamics simulations, we investigate here one of possible roles of supercoiling within topological domains constituting interphase chromosomes of higher eukaryotes. We analysed how supercoiling affects the interaction between enhancers and promoters that are located in the same or in...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Benedetti, Fabrizio, Dorier, Julien, Stasiak, Andrzej
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176356/
https://ncbi.nlm.nih.gov/pubmed/25123662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku759
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