The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1

Single-stranded DNA (ssDNA) at DNA ends is an important regulator of the DNA damage response. Resection, the generation of ssDNA, affects DNA damage checkpoint activation, DNA repair pathway choice, ssDNA-associated mutation and replication fork stability. In eukaryotes, extensive DNA resection requ...

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Detalles Bibliográficos
Main Authors: Ngo, Greg H.P., Balakrishnan, Lata, Dubarry, Marion, Campbell, Judith L., Lydall, David
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
Assuntos:
Genome Integrity, Repair and Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176354/
https://ncbi.nlm.nih.gov/pubmed/25122752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku746
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