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The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1
Single-stranded DNA (ssDNA) at DNA ends is an important regulator of the DNA damage response. Resection, the generation of ssDNA, affects DNA damage checkpoint activation, DNA repair pathway choice, ssDNA-associated mutation and replication fork stability. In eukaryotes, extensive DNA resection requ...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4176354/ https://ncbi.nlm.nih.gov/pubmed/25122752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku746 |
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