Essential role of eIF5-mimic protein in animal development is linked to control of ATF4 expression

Translational control of transcription factor ATF4 through paired upstream ORFs (uORFs) plays an important role in eukaryotic gene regulation. While it is typically induced by phosphorylation of eIF2α, ATF4 translation can be also induced by expression of a translational inhibitor protein, eIF5-mimi...

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Autori principali: Hiraishi, Hiroyuki, Oatman, Jamie, Haller, Sherry L., Blunk, Logan, McGivern, Benton, Morris, Jacob, Papadopoulos, Evangelos, Gutierrez, Wade, Gordon, Michelle, Bokhari, Wahaj, Ikeda, Yuka, Miles, David, Fellers, John, Asano, Masayo, Wagner, Gerhard, Tazi, Loubna, Rothenburg, Stefan, Brown, Susan J., Asano, Katsura
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
Soggetti:
Gene regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176352/
https://ncbi.nlm.nih.gov/pubmed/25147208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku670
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