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Rolling circle replication requires single-stranded DNA binding protein to avoid termination and production of double-stranded DNA

In rolling circle replication, a circular template of DNA is replicated as a long single-stranded DNA concatamer that spools off when a strand displacing polymerase traverses the circular template. The current view is that this type of replication can only produce single-stranded DNA, because the on...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ducani, Cosimo, Bernardinelli, Giulio, Högberg, Björn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176320/
https://ncbi.nlm.nih.gov/pubmed/25120268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku737
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