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Enzymatic Production of Monoclonal Stoichiometric Single-Stranded DNA Oligonucleotides

Single-stranded oligonucleotides are important as research tools as probes for diagnostics and gene therapy. Today, production of oligonucleotides is done via solid-phase synthesis. However, the capabilities of current polymer chemistry are limited in comparison to what can be produced in biological...

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Detalhes bibliográficos
Main Authors: Ducani, Cosimo, Kaul, Corinna, Moche, Martin, Shih, William M., Högberg, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843646/
https://ncbi.nlm.nih.gov/pubmed/23727986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2503
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