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Discovery of Novel-Scaffold Monoamine Transporter Ligands via in Silico Screening with the S1 Pocket of the Serotonin Transporter

[Image: see text] Discovery of new inhibitors of the plasmalemmal monoamine transporters (MATs) continues to provide pharmacotherapeutic options for depression, addiction, attention deficit disorders, psychosis, narcolepsy, and Parkinson’s disease. The windfall of high-resolution MAT structural info...

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Detalhes bibliográficos
Main Authors: Nolan, Tammy L., Geffert, Laura M., Kolber, Benedict J., Madura, Jeffry D., Surratt, Christopher K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176318/
https://ncbi.nlm.nih.gov/pubmed/25003748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500133b
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