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The Duplicated α7 Subunits Assemble and Form Functional Nicotinic Receptors with the Full-length α7
The α7 nicotinic acetylcholine receptor gene (CHRNA7) is linked to schizophrenia. A partial duplication of CHRNA7 (CHRFAM7A) is found in humans on 15q13–14. Exon 6 of CHRFAM7A harbors a 2-bp deletion polymorphism, CHRFAM7AΔ2bp, which is also associated with schizophrenia. To understand the effects o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4176222/ https://ncbi.nlm.nih.gov/pubmed/25056953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.582858 |
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