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Excessive Hyaluronan Production Promotes Acquisition of Cancer Stem Cell Signatures through the Coordinated Regulation of Twist and the Transforming Growth Factor β (TGF-β)-Snail Signaling Axis

The cancer stem cell (CSC) model suggests that a small subpopulation of cancer cells possesses the ability to self-renew and give rise to malignant progeny that drive cancer progression. Recent reports have also proposed the existence of certain extra- or intracellular signals that allow cancer prog...

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Detalhes bibliográficos
Main Authors: Chanmee, Theerawut, Ontong, Pawared, Mochizuki, Nobutoshi, Kongtawelert, Prachya, Konno, Kenjiro, Itano, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176217/
https://ncbi.nlm.nih.gov/pubmed/25077968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.564120
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