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Hypotonicity Stimulates Potassium Flux through the WNK-SPAK/OSR1 Kinase Cascade and the Ncc69 Sodium-Potassium-2-Chloride Cotransporter in the Drosophila Renal Tubule

The ability to osmoregulate is fundamental to life. Adult Drosophila melanogaster maintain hemolymph osmolarity within a narrow range. Osmolarity modulates transepithelial ion and water flux in the Malpighian (renal) tubules of the fly, which are in direct contact with hemolymph in vivo, but the mec...

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מידע ביבליוגרפי
Main Authors: Wu, Yipin, Schellinger, Jeffrey N., Huang, Chou-Long, Rodan, Aylin R.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176205/
https://ncbi.nlm.nih.gov/pubmed/25086033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.577767
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