Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice

Mutations in Leucine-Rich Repeat Kinase-2 (LRRK2) result in familial Parkinson's disease and the G2019S mutation alone accounts for up to 30% in some ethnicities. Despite this, the function of LRRK2 is largely undetermined although evidence suggests roles in phosphorylation, protein interaction...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Beccano-Kelly, Dayne A., Kuhlmann, Naila, Tatarnikov, Igor, Volta, Mattia, Munsie, Lise N., Chou, Patrick, Cao, Li-Ping, Han, Heather, Tapia, Lucia, Farrer, Matthew J., Milnerwood, Austen J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176085/
https://ncbi.nlm.nih.gov/pubmed/25309331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00301
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados