APOE ε variants increase risk of warfarin-related intracerebral hemorrhage

OBJECTIVE: We aimed to assess the effect of APOE ε variants on warfarin-related intracerebral hemorrhage (wICH), evaluated their predictive power, and tested for interaction with warfarin in causing wICH. METHODS: This was a prospective, 2-stage (discovery and replication), case-control study. wICH...

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Main Authors: Falcone, Guido J., Radmanesh, Farid, Brouwers, H. Bart, Battey, Thomas W.K., Devan, William J., Valant, Valerie, Raffeld, Miriam R., Chitsike, Lennox P., Ayres, Alison M., Schwab, Kristin, Goldstein, Joshua N., Viswanathan, Anand, Greenberg, Steven M., Selim, Magdy, Meschia, James F., Brown, Devin L., Worrall, Bradford B., Silliman, Scott L., Tirschwell, David L., Flaherty, Matthew L., Martini, Sharyl R., Deka, Ranjan, Biffi, Alessandro, Kraft, Peter, Woo, Daniel, Rosand, Jonathan, Anderson, Christopher D.
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176027/
https://ncbi.nlm.nih.gov/pubmed/25150286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000816
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