APOE ε variants increase risk of warfarin-related intracerebral hemorrhage

OBJECTIVE: We aimed to assess the effect of APOE ε variants on warfarin-related intracerebral hemorrhage (wICH), evaluated their predictive power, and tested for interaction with warfarin in causing wICH. METHODS: This was a prospective, 2-stage (discovery and replication), case-control study. wICH...

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Autors principals: Falcone, Guido J., Radmanesh, Farid, Brouwers, H. Bart, Battey, Thomas W.K., Devan, William J., Valant, Valerie, Raffeld, Miriam R., Chitsike, Lennox P., Ayres, Alison M., Schwab, Kristin, Goldstein, Joshua N., Viswanathan, Anand, Greenberg, Steven M., Selim, Magdy, Meschia, James F., Brown, Devin L., Worrall, Bradford B., Silliman, Scott L., Tirschwell, David L., Flaherty, Matthew L., Martini, Sharyl R., Deka, Ranjan, Biffi, Alessandro, Kraft, Peter, Woo, Daniel, Rosand, Jonathan, Anderson, Christopher D.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176027/
https://ncbi.nlm.nih.gov/pubmed/25150286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000816
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