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Expanding the Epigenetic Landscape: Novel Modifications of Cytosine in Genomic DNA

Methylation of the base cytosine in DNA is critical for silencing endogenous retroviruses, regulating gene expression, and establishing cellular identity, and has long been regarded as an indelible epigenetic mark. The recent discovery that the ten eleven translocation (TET) proteins can oxidize 5-m...

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書誌詳細
主要な著者: Kriaucionis, Skirmantas, Tahiliani, Mamta
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176005/
https://ncbi.nlm.nih.gov/pubmed/25274704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a018630
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