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Expanding the Epigenetic Landscape: Novel Modifications of Cytosine in Genomic DNA

Methylation of the base cytosine in DNA is critical for silencing endogenous retroviruses, regulating gene expression, and establishing cellular identity, and has long been regarded as an indelible epigenetic mark. The recent discovery that the ten eleven translocation (TET) proteins can oxidize 5-m...

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Bibliografski detalji
Glavni autori: Kriaucionis, Skirmantas, Tahiliani, Mamta
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176005/
https://ncbi.nlm.nih.gov/pubmed/25274704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a018630
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