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PARP inhibitors: current status and implications for anticancer therapeutics

Poly(ADP-ribose) polymerases (PARPs) comprise of a large family of 17 proteins encoded by various genes which participate in genome maintenance, apoptosis, inflammatory responses and the regulation of gene expression programs. PARP inhibitors, as therapeutic agents, come into play acting on both PAR...

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Hlavní autoři: Usmani, Hadi, Hussain, Syed Ather, Sheikh, Asfandyar
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175919/
https://ncbi.nlm.nih.gov/pubmed/24289880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-9378-8-46
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