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L-Proline catalyzed one-step synthesis of 4,5-diaryl-2H-1,2,3-triazoles from heteroaryl cyanostilbenes via [3+2] cycloaddition of azide

Use of a novel reagent has been established for the synthesis of a series of 4,5-diaryl-2H-1,2,3-triazoles (6a-i and 9a-e) from cyanostilbene analogs of benzo[b]thiophene, benzo[b]furan and indole, catalyzed by L-proline via Lewis base-catalyzed one-step [3+2]cycloaddition of azide. This method prov...

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Autori principali: Penthala, Narsimha Reddy, Madadi, Nikhil Reddy, Janganati, Venumadhav, Crooks, Peter A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175744/
https://ncbi.nlm.nih.gov/pubmed/25267862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2014.08.027
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