A molecular mechanism of mitotic centrosome assembly in Drosophila

Centrosomes comprise a pair of centrioles surrounded by pericentriolar material (PCM). The PCM expands dramatically as cells enter mitosis, but it is unclear how this occurs. In this study, we show that the centriole protein Asl initiates the recruitment of DSpd-2 and Cnn to mother centrioles; both...

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Detalhes bibliográficos
Main Authors: Conduit, Paul T, Richens, Jennifer H, Wainman, Alan, Holder, James, Vicente, Catarina C, Pratt, Metta B, Dix, Carly I, Novak, Zsofia A, Dobbie, Ian M, Schermelleh, Lothar, Raff, Jordan W
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175739/
https://ncbi.nlm.nih.gov/pubmed/25149451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03399
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